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Phenyl-2-nitropropene (Pn2p)

$25.00 per unit for buying at least 100
$25.00 / g

$1.00 per unit for buying at least 500
$1.00 / g


Phenyl-2-nitropropene is a chemical compound with the chemical formula is C9H9NO2. It can be produced by the reaction of benzaldehyde and nitroethane in the presence of a basic catalyst. In this reaction, the base deprotonates nitroethane to form a resonance stabilized anion. This anion nucleophilically adds to the aldehyde forming a beta nitro alcohol, which is subsequently dehydrated to yield the nitroalkene. This reaction is known as a nitroaldol reaction. Phenyl-2-nitropropene is used to make pharmaceuticals. It is used in pharmaceutical industry to manufacture drug Adderall, an amphetamine mixture, which is used to treat ADHD and narcolepsy.

Phenyl-2-Nitropropene : 1 mol benzaldehyde, 1.2 mol nitroethane and 15 mL diluted aqueous methylamine in 150 mL alcohol. Stirred and slightly heated for ca 4 hours. The reaction mixture is brought over into a beaker and cooled in the fridge (4°C). If precipitation doesn't commence at this point, water is poured in and the mixture put back in the fridge. The P2NP oil layer will slowly (or sometimes quickly) start forming a crystalline layer. If it doesn't, scratching the wall with e.g. a glass rod will help. If even this won't help, it means you probably fucked something up. The yields I have had using this "adaptation": 81% (i-PrOH), 79% (i-PrOH), 75% (EtOH) and 71% (EtOH) (yields calculated after crystallizing once; I store my crystals in the freezer and also recrystallize them prior to use).

n2p by the use of Zinc activated with a temperature of 140-150 degred Celcius for 3 hr under N2 athmosphere... This compound shold take hard on a double bound and since Fe could be used to reduce pn2p to ketone maybe this activated Zn could do the same?? Has Anyone out there tryed this? I have done it but im not shure about the results, the reaction was wery exotermic and the solution turned red and thick and gasses of nitrogenoxide

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$1.00 per unit for buying at least 500 Phenyl-2-nitropropene (Pn2p)

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Welcome to Biopure Pharmaceutical the longest standing, and most trusted suppliers of research chemicals, legal steroids andother pharmaceutical products in the US and Europe.

We have been in the business of supplying the US, UK and the rest of Europe with research chemicals for academic and Institutional research projects for some time and have now opened a website to complement our ever growing business needs...Read More

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